Pavlos Prosalentis, junior came from a family with a strong artistic tradition. He was the grandson of the renowned sculptor Pavlos Prosalentis (senior) and son of painter Spyridon Prosalentis. His siblings were the painters Emilios, Eleni and Olga Prosalentis.

He studied at The School of Fine Arts in Napoli in the studio of D. Morelli and then continued his studies in Paris.

For a long period Pavlos Prosalentis, junior lived in Egypt where he painted a large number of his works. Like that of his peers of the period, his work is defined by academism. His subject matter was inspired by everyday life in the East making him one of the important Greek orientalist artists.

His work is found in many public and private collections, notably that of: The National Gallery, Athens; The Athens Municipal Gallery; The Averoff Gallery; The Koutlides Collection and The National Bank of Greece collection.