Victor Ioannides' themes derive from scenes of everyday life such as landscape, still life and portraiture. Technique was of great importance to Ioannides, as was use of materials. He made his own varnishes using turpentine, mastic and caoutchouc as a base, mixing the components over a fire. Sometimes, particularly in his still life paintings, before adding the colours, he created a relief surface base from alabaster powder on the canvas. Then he used the processed paints and varnishes, thus giving the painted surfaces a porcelain like effect.

In 1963, Ioannides represented Cyprus at The Alexandria Biennale, the occasion being the first time the Republic of Cyprus officially participated in an international exhibition. From 1960 to 1973 he participated in all Panhellenic Art Exhibitions.

His work can be found in many public and private collections in Cyprus. Notably at The State Gallery of Contemporary Cypriot Art, The Nicosia Municipality Collection, The Leventis Gallery, The Bank of Cyprus Cultural Centre and The Central Bank of Cyprus Art Collection.