Germenis was born in Kefalonia. He attended his first art lessons at The Corfu School of Art.

In 1915, he moved to Athens and enrolled at The Aristotle University, to study Law and simultaneously at The School of Fine Arts to study painting under Spyros Vikatos, Georgios Jakobides and Georgios Roilos, and sculpture under Thomopoulos. In his third year, he discontinued his law studies so that he could focus fully on art.

In around 1955 he moved to Ethiopia and became the court painter of the Emperor Haile Selassie. He remained in Addis Ababa for five years.

Germenis’ themes include portrait, landscape, seascape and compositional where his style moves between realism and expressionism.

His work can be found in: The National Gallery of Greece, The Municipal Gallery of Athens, The Leventis Gallery, The Averoff Gallery, The Bank of Greece and many other public and private collections.