Nikitas Grispos was born on the island of Amorgos in 1873.

He studied at the School of Fine Arts, Athens under Nikiforos Lytras, Spyridon Prosalentis and Constantinos Volanakis. In parallel, he attended sculpture lessons.

His themes included landscape, still-life, portraiture and symbolism, while his painting was in keeping with the academic tradition but also employed an impressionistic feeling.

Between 1920 and 1940 he taught in secondary education and from 1926 onwards at the newly founded Art School in Volos.

He held many solo shows and participated in prestigious group exhibitions such as 1939, 1948, 1952, 1960, 1963, 1967, 1971, 1973 Pan-Hellenic Exhibitions.

His work is found in many public and private collections in Greece, notably: The National Gallery of Greece, the Athens Municipal Gallery, the Volos Municipal Gallery and the Koutlides Collection.